Dietary Supplement. 1000 mg MSM & 500 mg Glucosamine. In one convenient tablet. Optimum Nutrition 's MSM plus Glucosamine is made with a synergistic blend of Methylsulfonylmethane (MSM) and Glucosamine Sulfate. MSM is a bioavailable sulfur compound that occurs naturally in a wide variety of unprocessed food items. Sulfur is an integral component of various amino acids, vitamins, antioxidant compounds, coenzymes and hormones. Sulfur also contributes to the formation of double bonds that give rise to the structural characteristics of collagen, glucosamine and numerous proteins. MSM plus Glucosamine is produced and packaged in accordance with current Good Manufacturing Practices (cGMP's) in our own state-of-the-art, OTC approved facility.